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Cannabis Profiles

TCM
 

Dopaminergic regulator. promotes homeostasis of the neurotransmitter dopamine.

dopamine regulator

Endorphinergic. agents involved in the synthesis or activation of endorphins.

endorphin white

Type I: Almost no CBD

Type II: CBD > 2%

Type III: CBD >= THC

Terpinolene-Caryophyllene-Myrcene

Type I: Almost no CBD

Type II: CBD > 2%

Type III: CBD >= THC

Terpene Profile for type 1 cannabis
Rated 5 out of 5
5 out of 5 stars (based on 1 review)
noon
evening
Primary Benefits
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Motivation
Focus
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Rest
Applications
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Burnout
Detox
Description

The Terpinolene Caryophyllene Myrcene terpene profile supports dopamine & noradrenaline levels, regulates dopamine, and promotes GABA/serotonin activity. Read on to learn how these effects can change your response to stress.

According to a 2018 study published in the Journal of Pharmacy and Pharmacology, the pain-reducing effects of terpinolene can be attributed in-part to influences on endorphin receptors [1]. Increasing endorphins indirectly raises dopamine levels, which may promote motivation & focus.

Caryophyllene has the potential to regulate dopamine activity by rescuing dopaminergic neurons from oxidative stress, a hallmark of many substance use disorders. According to a recent review by the College of Medicine, UAE, caryophyllene may have applications for addressing addictions and some types of depression [2]. Caryophyllene is also a α2-adrenergic receptor agonist, which inhibits the release of noradrenaline [3]. This makes caryophyllene a potential candidate for addressing hypertension.

Many cannabis cultivars with high amounts of terpinolene will also have a considerable amount of ocimene. And while ocimene is not known to directly affect any specific neurotransmitter system, it has been shown in lab studies to have anti-oxidant and anti-inflammatory properties [4]. This actually bodes well for the ‘effect profile’ of TCM, since dopaminergic neurons are especially susceptible to damage from oxidative stress.

If you’re lucky enough to find the TCM profile with a decent amount of myrcene (some terpinolene-dominant cultivars produce only a modest amount), then you could be feeling relaxed & content by the time the effects of terpinolene wear off. If you decided to put that boost of dopamine to good use, you just might be ready to chill & unwind anyway.

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Cannabinoids
Terpenes
Common Cultivars

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Reviews

Rated 5 out of 5
April 21, 2023

A great choice for mornings that require a lot of planning.

John
Legend

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Johnathan Kobé
Founder - DREAM BIG
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Johnathan Kobé
Founder - DREAM BIG
Learn how you can overcome burnout, fuel your creativity, and find your focus with cannabis & natural supplementation.
Discover how the DREAM BIG Program can help you master your mood & mindset.
Signup to receive 3 short introduction videos. Unsubscribe anytime.
Use this checklist to guide your journey.
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These icons appear on items to indicate the affected neurotransmitter(s).
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Dopaminergic. promotes the synthesis or activity of dopamine.

Endorphinergic. promotes the synthesis or activity of endorphins.

noradrenergic

Noradrenergic. promotes the synthesis or activity of noradrenaline.

Cholinergic. promotes the synthesis or activity of acetylcholine.

gabanergic

GABAnergic. promotes the synthesis or activity of GABA.

Serotonergic. promotes the synthesis or activity of serotonin.

These icons appear on items to indicate the optimal time-of-day.
rising

Rising. sunrise to mid-morning.

2-midmorning

Morning. mid-morning to noon.

3-noon

Noon. noon to mid-afternoon.

5-sunset

Afternoon. mid-afternoon to sunset.

evening

Evening. sunset to bedtime.

These icons appear on items to indicate additional benefits & important alerts.

Synergistic. combining with another supplement may increase potency.

Methylation agent. increases or decreases methylation of neurotransmitters.

Cortisol modulator. affects the synthesis or activity of the stress hormone cortisol.

Glucose regulator. attenuates changes in blood sugar levels.