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Supplement details

Cannabidiol

Dopaminergic stabilizer. promotes balance between the upregulation and downregulation of dopamine.

dopamine regulator

Serotonergic. involved in the production or activation of serotonin.

serotoneric
augmentor

afternoon
(mid-afternoon to sunset)

evening
(sunset to bedtime)

Summary

"Cannabidiol, also known as CBD, is an antipsychotic cannabinoid found in the hemp plant Cannabis sativa...CBD alone is not intoxicating, but it appears to affect the euphoric effect of THC (which is an isomer of cannabidiol) and add a sedative quality...Medically, it appears to relieve convulsion, inflammation, anxiety, and nausea, as well as inhibit cancer cell growth."

“Cannabidiol - Wikidoc.” Wikidoc.org, 2012, www.wikidoc.org/index.php/Cannabidiol.

Benefits
1.
May improve symptoms of anxiety by increasing serotonin transmission [1]
2.
Reduces withdrawal symptoms caused by dopamine dysregulation [2]
3.
Improves the efficacy of THC while reducing/preventing psychotic side-effects such as anxiety and paranoia [3]
Deficiency Factors

Access a list of other supplements that enhance the benefits of Cannabidiol when you signup for a support plan.

Applications & Precautions
Applications
Alcohol Detox, Caffeine Detox, Sugar Detox
Precautions
Taking large doses of CBD can lead to drowsiness, especially late in the day.
Dosage Guidelines
Dosing Range
25
-
50
mg
Dose Increment
25
mg
Maximum Daily
150
mg
Best absorbed
sublingually
Recommended Products

See a list of verified product recommendations for Cannabidiol when you signup for a support plan.

1. 
De Gregorio, Danilo, et al. “Cannabidiol Modulates Serotonergic Transmission and Reverses Both Allodynia and Anxiety-like Behavior in a Model of Neuropathic Pain.” Pain, vol. 160, no. 1, 27 Aug. 2018, pp. 136–150, www.ncbi.nlm.nih.gov/pmc/articles/PMC6319597/, 10.1097/j.pain.0000000000001386.
2. 
Seeman, P. “Cannabidiol Is a Partial Agonist at Dopamine D2High Receptors, Predicting Its Antipsychotic Clinical Dose.” Translational Psychiatry, vol. 6, no. 10, Oct. 2016, pp. e920–e920, www.ncbi.nlm.nih.gov/pmc/articles/PMC5315552/, 10.1038/tp.2016.195.
3. 
Hudson, Roger, et al. “Cannabidiol Counteracts the Psychotropic Side-Effects of Δ-9-Tetrahydrocannabinol in the Ventral Hippocampus through Bidirectional Control of ERK1–2 Phosphorylation.” The Journal of Neuroscience, vol. 39, no. 44, 30 Sept. 2019, pp. 8762–8777, www.jneurosci.org/content/39/44/8762, 10.1523/jneurosci.0708-19.2019.

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Johnathan Kobé
Founder - DREAM BIG
Welcome to DREAM BIG! Learn how you can overcome anxiety, depression, & burnout with cannabis & natural supplements.
Johnathan Kobé
Founder - DREAM BIG
Welcome to DREAM BIG! Learn how you can overcome anxiety, depression, & burnout with cannabis & natural supplements.
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