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DL-Phenylalanine
 

Dopaminergic. involved in the synthesis or activation of dopamine.

dopaminergic

Endorphinergic. involved in the synthesis or activation of endorphins.

endorphin white
precursor
Summary

"DL-Phenylalanine is marketed as a nutritional supplement for its putative analgesic and antidepressant activities. The putative analgesic activity of DL-phenylalanine may be explained by the possible blockage by D-phenylalanine of enkephalin degradation by the enzyme carboxypeptidase A. The mechanism of DL-phenylalanine's putative antidepressant activity may be accounted for by the precursor role of L-phenylalanine in the synthesis of the neurotransmitters norepinephrine and dopamine."

“Phenylalanine - Wikidoc.” Wikidoc.org, 2022, www.wikidoc.org/index.php/Phenylalanine.

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Benefits
1.
increases beta-endorphin levels by blocking the degradation enzyme, carboxypeptidase A. [1]
2.
may increase available dopamine by providing the first-stage precursor phenylalanine. [2]
Deficiency Factors
dietary insufficiency

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Applications
Alcohol Detox, Burnout
Dosage Guidelines
Dosing Range
500
-
1500
mg
Dose Increment
500
mg
Maximum Daily
6000
mg
Best absorbed
without food
Recommended Products

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1. 
Walsh. “Analgesic Effectiveness of D-Phenylalanine in Chronic Pain Patients.” Archives of Physical Medicine and Rehabilitation, vol. 67, no. 7, 2021, pubmed.ncbi.nlm.nih.gov/3524509/.
2. 
Nutrient Metabolism. Elsevier, 2003, www.sciencedirect.com/book/9780124177628/nutrient-metabolism.
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Dopaminergic. promotes the synthesis or activity of dopamine.

Endorphinergic. promotes the synthesis or activity of endorphins.

noradrenergic

Noradrenergic. promotes the synthesis or activity of noradrenaline.

Cholinergic. promotes the synthesis or activity of acetylcholine.

gabanergic

GABAnergic. promotes the synthesis or activity of GABA.

Serotonergic. promotes the synthesis or activity of serotonin.

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Noon. noon to mid-afternoon.

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Afternoon. mid-afternoon to sunset.

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Evening. sunset to bedtime.

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Synergistic. combining with another supplement may increase potency.

Methylation agent. increases or decreases methylation of neurotransmitters.

Cortisol modulator. affects the synthesis or activity of the stress hormone cortisol.

Glucose regulator. attenuates changes in blood sugar levels.