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Licorice Root
 

Dopaminergic upregulator. stimulates the production or activity of dopamine.

dopamine upregulator

Noradrenergic. involved in the synthesis or activation of noradrenaline.

noradrenergic

Serotonergic. involved in the production or activation of serotonin.

serotoneric
augmentor

Cortisol modulator

Summary
Benefits
1.
Serves as a MAO-A inhibitor to slow the breakdown of dopamine, noradrenaline, and serotonin [1]
2.
Inhibits the conversion of cortisol to cortisone, which may alleviate fatigue due to impaired adrenal function [2]
Deficiency Factors

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Applications & Precautions
Applications
Burnout, Sugar Detox
Precautions
Excessive dosing may lead to high blood pressure and/or restlessness.

Avoid use while on a ketogenic diet; licorice root's effect on blood sugar may not be suitable for ketosis.
Dosage Guidelines
Dosing Range
500
-
500
mg
Dose Increment
500
mg
Maximum Daily
1000
mg
Best absorbed
with food
Recommended Products

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add to supplement stack
add to supplement stack
1. 
Prajapati, Ritu, et al. “Isoliquiritigenin, a Potent Human Monoamine Oxidase Inhibitor, Modulates Dopamine D1, D3, and Vasopressin V1A Receptors.” Scientific Reports, vol. 11, no. 1, Dec. 2021, www.nature.com/articles/s41598-021-02843-6, 10.1038/s41598-021-02843-6.
2. 
Methlie, Paal, et al. “Grapefruit Juice and Licorice Increase Cortisol Availability in Patients with Addison’s Disease.” European Journal of Endocrinology, vol. 165, no. 5, Bioscientifica, Nov. 2011, pp. 761–769. Crossref, doi:10.1530/eje-11-0518.
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Johnathan Kobé
Founder - DREAM BIG
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Discover how the DREAM BIG Program can help you master your mood & mindset.
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These icons appear on items to indicate the affected neurotransmitter(s).
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Dopaminergic. promotes the synthesis or activity of dopamine.

Endorphinergic. promotes the synthesis or activity of endorphins.

noradrenergic

Noradrenergic. promotes the synthesis or activity of noradrenaline.

Cholinergic. promotes the synthesis or activity of acetylcholine.

gabanergic

GABAnergic. promotes the synthesis or activity of GABA.

Serotonergic. promotes the synthesis or activity of serotonin.

These icons appear on items to indicate the optimal time-of-day.
rising

Rising. sunrise to mid-morning.

2-midmorning

Morning. mid-morning to noon.

3-noon

Noon. noon to mid-afternoon.

5-sunset

Afternoon. mid-afternoon to sunset.

evening

Evening. sunset to bedtime.

These icons appear on items to indicate additional benefits & important alerts.

Synergistic. combining with another supplement may increase potency.

Methylation agent. increases or decreases methylation of neurotransmitters.

Cortisol modulator. affects the synthesis or activity of the stress hormone cortisol.

Glucose regulator. attenuates changes in blood sugar levels.